He picks her up as she's released from prison. We learn that she's been locked up six months, but why? House knows the legally indicated charges - mis-prescription of drugs - but there's obviously more, and he and we go on a journey of unraveling the mystery.
Its revelation - that she put her brother to death, at his request, to put him out of the pain of progressed Huntington's - is sad and satisfying as a motivation for her actions. She laments to House that there's no one in her family to perform that service for her.
House takes this as an implicit plea for his help, though it's not clear if that's what 13 intended. In previous House years, any such pleas, implicit or explicit, would have fallen on deaf ears. Until this year, House cared only or mainly for himself.
He's still pretty selfish, but his love for Cuddy has humanized him, somewhat. And so he tells 13 at the end that she can count on him to help her - "I'll kill you," he says to her - if that's what she wants.
It's just like House the series and House the man to show his humanity by agreeing to take someone's life in these circumstances. But House is also a genius, and I'd like to see him do the impossible by coming up with a cure for 13's illness.
See also House and Cuddy on the Other Side in Season 7 Premiere ... House 7.2: House and Cuddy, Chapter 2 ... House 7.3: The Author and the White Lie ... House 7.9: The Vilda Chaya ... House 7.11: The Patient's Most Important Right ... House 7.14: House, Death, and Cuddy ... House 7.16: Broken Hearts and their Repair ... House 7.17: Deadly Healthy Diet
And see also House Reborn in Season Six? ... 6.2: The Gang is Back and Fractured ... 6.3: The Saving Hitler Quandary ... 6.4: Diagnosis vs. Karma ... 6.5 Getting Better ... 6.6 House Around the Bases ... Four's a Crowd on House 6.7 ... House 6.8 and the Reverse of Flowers for Algernon ... House 6.9: Wilson ... House 6.10: Back in Business ... House 6.11: Making Amends, Mending Fences, and a Psychopath ... House 6.12: The Progression to Mensch ... House 6.13: Cuddy's Perspective ... House Meets Blogger in 6.14 ... House 6.15: About Taub ... House 6.16: Revealing Couples ... House 6.17: Socrates on Steroids ... House 6.18: Open Marriage
The Plot to Save Socrates
"a Da Vinci-esque thriller" - New York Daily News
"Sierra Waters is sexy as hell" - curled up with a good book